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Post 0

Friday, December 28, 2007 - 4:07pmSanction this postReply
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Inspired by the Foreign Policy/Self-Defense/Bidinotto's Facts thread ...

Prozac's approval was rushed

Most of the approval committee was getting $$$ from it's maker, Eli Lilly

Dissent in the approval committee was stifled

Prozac's natural, serotonin-increasing, competitor, tryptophan -- after being used safely by several thousand folks for decades -- got 1500 sick and 38 dead; by causing EMS

A main Japanese exporter of tryptophan had changed lab procedures when Prozac had been improved -- leading to 2 contaminated batches; headed directly for the US

The FDA pulled tryptophan from the market

No other country did -- and no other countries had any problem with supplemental tryptophan

Prozac was the most successful new U.S. drug in history

Even several years after the contamination was proved at fault, the FDA kept tryptophan off the market -- claiming that this amino acid that is essential to human life, could still be the cause of EMS

It was known that one of the best treatments for EMS is uncontaminated tryptophan -- but tryptophan wasn't given to those suffering from it (and they were, instead, paraded into court rooms to tell their sob stories) 

As Prozac's patent was expiring, the FDA "silently" (i.e., in the middle of an another, unrelated report) re-allowed the commercial sale of tryptophan in the U.S.

Real Conspiracy?: You decide.

;-)

Ed




Post 1

Friday, December 28, 2007 - 4:37pmSanction this postReply
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Here are a couple more ...

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Richard Wurtman of MIT gave conferences meant to outlaw the commercial sale of amino acids

His wife wrote a book promoting SSRI's, serotonin-increasing drugs which have natural competition in a free market -- i.e., the amino acid, tryptophan

Richard Wurtman, while extolling the dangers of ingesting amino acids (including tryptophan) -- had already acquired several "use-patents" for the ingestion of amino acids , the very amino acids that he was claiming were too dangerous to ingest. His use-patents would take effect only if he could convince others that the amino acids needed to be pulled from the market -- and made into Rx-only products
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A lawyer for the food giant, Monsanto, took a job with the governing body that oversees modified foods

... and went back to Monsanto ...

... and went back to the government ...

... and, after having successfully-effected a precise change in the laws regarding modified foods -- a change that benefitted Monsanto at the expense of its competitors) -- went back to Monsanto
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Real Conspiracies?: You decide.

Ed




Post 2

Thursday, January 3 - 12:13pmSanction this postReply
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Need more clues to decide? Try these (from PubMed) ...

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An investigation of the cause of the eosinophilia-myalgia syndrome associated with tryptophan use. N Engl J Med. 1990 Aug 9;323(6):357-65.

Division of Field Services, Centers for Disease Control, Minneapolis, MN.
... CONCLUSIONS. The outbreak of the eosinophilia-myalgia syndrome in 1989 resulted from the ingestion of a chemical constituent that was associated with specific tryptophan-manufacturing conditions at one company. The chemical constituent represented by peak E may contribute to the pathogenesis of the eosinophilia-myalgia syndrome, or it may be a surrogate for another chemical that induces the syndrome.
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... and, over a decade later ...

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Luteal phase administration of agents for the treatment of premenstrual dysphoric disorder. CNS Drugs. 2004;18(7):453-68.

Departments of Obstetrics/Gynecology and Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
... Symptom reduction with tryptophan was significantly greater than with placebo, but the availability of this medication is strictly limited because of safety concerns. ...
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Even over a decade after the discovery of the contamination of tryptophan as the cause of EMS, the availibility of this tryptophan was "strictly limited because of safety concerns." [??]

Yeah, right. Tell me, have there ever been any other products -- e.g., Perrier, Tylenol, etc -- which were held off of the market for over a decade (in this case, the expiration time of the patent for a drug which competes with it) AFTER THEY had been found to be contaminated?

No answer? Hmm ... interesting train of events.

Ed




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