Stephen Hawking suggests that asking, "What happened before the Big Bang?" might be like asking, "What is north of the North Pole?" He suggests -- as did Einstein -- that we can't think of time as a straight line, since it time is relative to velocity and mass and we don't know what this means at the singularity in a black hole or at the "beginning" of our universe.
As to we humans begin insignificant, size is not the standard of significance. Luke is right to ask, "By what standard?" I understand that our lives as man qua man is the standard or value and thus a measure of significance.
As a serious amateur astronomer (I originally majored in the subject) I feel anything but insignificant when I gaze at the stars or study the latest discoveries about the structure of the cosmos. I'm filed with an excitement of being about to understand the universe, or aspects of it, and appreciates its beauty.
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